Metallo-β-lactamase inhibitory activity of 3-alkyloxy and 3-amino phthalic acid derivatives and their combination effect with carbapenem

Y Hiraiwa, A Morinaka, T Fukushima, T Kudo

Index: Hiraiwa, Yukiko; Morinaka, Akihiro; Fukushima, Takayoshi; Kudo, Toshiaki Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 18 p. 5841 - 5850

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Citation Number: 6

Abstract

Abstract 3-Alkyloxy and 3-amino phthalic acid derivatives were found to have metallo-β- lactamase inhibitory activity. Among them, 3-amino phthalic acid derivatives showed both potent activity against metallo-β-lactamase, IMP-1 inhibitory activity and a strong ...

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