The preparation of α-substituted, β-hydroxy piperidines and pyrrolidines: The total synthesis of febrifugine
LE Burgess, EKM Gross, J Jurka
Index: Burgess, Laurence E.; Gross, Elizabeth K. M.; Jurka, Joe Tetrahedron Letters, 1996 , vol. 37, # 19 p. 3255 - 3258
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Citation Number: 69
Abstract
Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Epoxides generated from cyclic ene carbamates are effective N-acyl iminium ion precursors and allow for the preparation of β-hydroxy, α-substituted piperidines and pyrrolidines. The total synthesis of racemic Febrifugine is also described. ... Epoxides generated from cyclic ene ...
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