Unusual behavior in the reactivity of 5-substituted-1H-tetrazoles in a resistively heated microreactor

…, T Razzaq, W Goessler, DM Roberge…

Index: Gutmann, Bernhard; Glasnov, Toma N.; Razzaq, Tahseen; Goessler, Walter; Roberge, Dominique M.; Kappe, C. Oliver Beilstein Journal of Organic Chemistry, 2011 , vol. 7, p. 503 - 517

Full Text: HTML

Citation Number: 13

Abstract

Abstract The decomposition of 5-benzhydryl-1H-tetrazole in an N-methyl-2- pyrrolidone/acetic acid/water mixture was investigated under a variety of high-temperature reaction conditions. Employing a sealed Pyrex glass vial and batch microwave conditions at 240 C, the tetrazole is comparatively stable and complete decomposition to diphenylmethane requires more than 8 h. Similar kinetic data were obtained in ...

Related Articles:

Reaction of diphenylketene with 1-methylbenzimidazole. A reinvestigation

[Haddadin, Makhluf J.; Murad, Hiba H. N. Journal of Organic Chemistry, 1980 , vol. 45, # 12 p. 2518 - 2519]

Design, synthesis and pharmacological evaluation of novel azole derivatives of aryl acetic acid as anti-inflammatory and analgesic agents

[Amir, Mohammad; Saifullah, Khalid; Akhter, Wasim Journal of Enzyme Inhibition and Medicinal Chemistry, 2011 , vol. 26, # 1 p. 141 - 148]

More Articles...