The reaction of hydrazine with some α-dimethylaminoacetophenones

RL Letsinger, R Collat

Index: Letsinger; Collat Journal of the American Chemical Society, 1952 , vol. 74, p. 621

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Citation Number: 11

Abstract

The hydrazone of a-dimethylaminoacetophenone may be prepared by refluxing a mixture of the ketone and 85% hydrazine hydrate for a short time. It decomposes when heated with potassium hydroxide to give N, N-dimethylphenethylamine, When the aminoketone is heated for a longer period of time with hydrazine hydrate, the amino goup is lost and acetophenone hydrazone is formed. Deamination occurs more readily with the ...