Synthesis

Organophosphorus esters of 1-hydroxy-2-phenylbenzimidazole: synthesis and utilization as novel peptide coupling reagents

ND Kokare, RR Nagawade, VP Rane, DB Shinde

Index: Kokare, Nagnnath D.; Nagawade, Rahul R.; Rane, Vipul P.; Shinde, Devanand B. Synthesis, 2007 , # 5 p. 766 - 772

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Citation Number: 17

Abstract

Abstract Highly efficient coupling reagents-phosphoric acid diethyl ester 2- phenylbenzimidazol-1-yl ester, diphenylphosphinic acid 2-phenylbenzimidazol-1-yl ester and phosphoric acid diphenyl ester 2-phenylbenzimidazol-1-yl ester-were designed, synthesized and successfully applied in peptide coupling reactions. Their efficiency was evaluated through the synthesis of a range of amides and peptides, and the extent of ...

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