Vollständig enantioselektive Inversion der Konfiguration von (S)??(+)??Carnitinen

I Bernabei, R Castagnani, F De Angelis…

Index: Bernabei, Ida; Castagnani, Roberto; Angelis, Francesco De; Witt Scalfaro, Paolo De; Giannessi, Fabio; et al. Angewandte Chemie, 1994 , vol. 106, # 20 p. 2202 - 2203

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Abstract

Abstract Tonnen von ungenutztem (s)-Carnitinamid 1 die bei der industriellen Herstellung des biologisch aktiven, pharmazeutisch bedeutsamen (R-Isomers 3 anfallen, können nun zu diesem umgesetzt werden. In formal fünf Stufen gelingt die Isomerisierung über das β- Lacton 2 in einer Gesamtausbeute von 80%.

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