Steroids

Tetrapropylammonium perruthenate as a mild and efficient oxidant for sensitive steroidal alcohols

CK Acosta, PN Rao, HK Kim

Index: Acosta, C. Kirk; Rao, Pemmaraju N.; Kim, Hyun K. Steroids, 1993 , vol. 58, # 5 p. 205 - 208

Full Text: HTML

Citation Number: 18

Abstract

Abstract Tetrapropylammonium perruthenate N-methylmorpholine N-oxide oxidation of steroidal alcohols is described. The reagent combination is mild and gave good yields of the corresponding ketones. Although the oxidation can generate ketones from 3-, 11-, 15-, 17-, and 20-hydroxy steroids, the oxidation of homoallylic alcohols proceeds in low yields. Finally, we observed that the oxidation reagents will convert 17α-hydroxy-2-keto steroids ...

Related Articles:

Expedient Method for Oxidation of Alcohol by Hydrogen Peroxide in the Presence of Amberlite IRA 400 Resin (Basic) as Phase??Transfer Catalyst

[Bhati, Nishi; Sarma, Kuladip; Goswami, Amrit Synthetic Communications, 2008 , vol. 38, # 9 p. 1416 - 1424]

Metal catalysis in oxidation by peroxides. 27. Anionic molybdenum-picolinate N-oxido-peroxo complex: an effective oxidant of primary and secondary alcohols in …

[Bortolini, O.; Campestrini, S.; Furia, F. Di; Modena, G.; Valle, G. Journal of Organic Chemistry, 1987 , vol. 52, # 24 p. 5467 - 5469]

Double bond migration over solid KOH suspended in aprotic solvents

[D'Incan, E.; Viout, P. Tetrahedron, 1984 , vol. 40, # 18 p. 3421 - 3424]

Oxidation of steroidal 5-en-3β-ols with Jones reagent in ether

[Solaja, Bogdan A.; Mili, Dragana R.; Do, Ljiljana I. Steroids, 1994 , vol. 59, # 5 p. 330 - 334]

Oxidative decyanation of secondary nitriles to ketones

[Freerksen, Robert W.; Selikson, Sandra J.; Wroble, Randall R.; Kyler, S. Keith; Watt, David S. Journal of Organic Chemistry, 1983 , vol. 48, # 22 p. 4087 - 4096]

More Articles...