The synthesis of some trifluoromethyl derivatives of p-aminobenzoic acid, sulfanilamide and p, p'-diamino diphenyl sulfone

WT Caldwell, AN Sayin

Index: Caldwell; Sayin Journal of the American Chemical Society, 1951 , vol. 73, p. 5125

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Citation Number: 9

Abstract

Comparatively few trifluoromethyl derivatives of compounds of recognized physiological or chemotherapeutic activity have been prepared. The strongly electronegative nature of the trifluoromethyl radical, its peculiar chemical stability and striking effect upon physical properties of compounds containing it, as exemplified in their low boiling points and melting points, impelled us to introduce it into a variety of substances, some of which are ...