Rationalisation of the stereochemical outcome of ene-reductase-mediated bioreduction of α, β-difunctionalised alkenes

…, A Manfredi, D Monti, F Parmeggiani, A Pugliese…

Index: Brenna, Elisabetta; Crotti, Michele; Gatti, Francesco G.; Manfredi, Alessia; Monti, Daniela; Parmeggiani, Fabio; Pugliese, Andrea; Zampieri, Davila Journal of Molecular Catalysis B: Enzymatic, 2014 , vol. 101, p. 67 - 72

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Citation Number: 8

Abstract

Abstract The OYE1-3-mediated reductions of some α, β-difunctionalised alkenes, showing on the double bond a nitrile and ester group, are submitted to a careful stereochemical analysis, in order to identify which of the two electron-withdrawing groups (EWGs) is responsible for the activation of the C double bond; length as m-dash

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