Design of integrated fluorescent estrogens: the second donor effect on absorption, fluorescence, and ground-state molecular orbital properties of trans-4, 4'- …

GM Anstead, JA Katzenellenbogen

Index: Anstead, Gregory M.; Katzenellenbogen, John A. Journal of Physical Chemistry, 1990 , vol. 94, # 4 p. 1328 - 1334

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Citation Number: 11

Abstract

In the design of inherently fluorescent ligands for the estrogen receptor, biological constraints limit to hydroxyl the functional groups that can be utilized as electron donors. In an attempt to optimize the fluorescent properties of such probes, we have studied the effect that a second alkoxy donor has on the fluorescence properties of two systems, peripherally located in a nitro-substituted diarylindene, and centrally located in a nitrostilbene. The ...

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