Aqueous solutions that model the cytosol: studies on polarity, chemical reactivity and enzyme kinetics

N Asaad, MJ Den Otter, JBFN Engberts

Index: Asaad, Nabil; Otter, Marie Jetta Den; Engberts, Jan B. F. N. Organic and Biomolecular Chemistry, 2004 , vol. 2, # 9 p. 1404 - 1412

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Citation Number: 13

Abstract

Concentrated solutions of a series of organic compounds have been prepared and the effects of these solutes on the properties of the solvent system assessed as a function of their concentration and nature. Polarity, as measured by Reichardt's ET (30) probe, exhibits a linear variation with both solute and water concentration for simple solutes. Non-linear behaviour was also observed and is associated with preferential solvation or binding of ...