Synthesis of bridgehead fluorobicyclo [2.2. 2] octanes

J Kopecký, J Šmejkal

Index: Kopecky, Jan; Smejkal, Jaroslav Collection of Czechoslovak Chemical Communications, 1980 , vol. 45, # 11 p. 2971 - 2975

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Citation Number: 8

Abstract

Introduction of methods for measurement of chemical shifts by 19F-NMR caused that 1 and/or 4-fluorobicyclo[2.2.2]octanes became a useful group of compounds, because the mentioned method allows to study on this model the influence of non- conjugation polar effects and their transmission to the reaction centre1 ,2 as well as the through-bond interactions3 .4. As the synthetical accessibility of the bridgehead fiuorobicyclo[2.2.2]octanes has been relatively difficult so ...