Synlett

YCl3-Catalyzed Highly Selective Conversion of Arylglyoxal to α-Aryl-α-Hydroxyacetic Ester: Dramatic Influence of Base

PR Likhar, AK Bandyopadhyay

Index: Likhar, Pravin R.; Bandyopadhyay, Ananda K. Synlett, 2000 , # 4 p. 538 - 540

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Citation Number: 8

Abstract

Abstract: Yttrium chloride catalyzed reaction of arylglyoxal and alcohol resulted in highly selective formation of a-aryl-a-hydroxyacetic ester under the influence of an added base (triethylamine, pyridine, piperidine) and afforded acetal in the absence of the base. The possible role of the additive (base) is discussed. Key words: lanthanide catalysis, 1, 2- hydride shift, mandelic ester, yttrium chloride, aryl glyoxal

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