A New One??Pot Synthetic Approach to the Highly Functionalized (Z)??2??(Buta??1, 3??dienyl) phenols and 2??Methyl??2H??chromenes: Use of Amine, Ruthenium and Base …

…, VV Narayana, K Ramakumar

Index: Ramachary, Dhevalapally B.; Ramakumar, Kinthada; Narayana, Vidadala V. Journal of Organic Chemistry, 2007 , vol. 72, # 4 p. 1458 - 1463

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Citation Number: 12

Abstract

Abstract A practical and simple one-pot multi-catalysis process for the synthesis of highly substituted benzo [b] oxepines 5,(Z)-2-(buta-1, 3-dienyl) phenols 6 and 2-methyl-2H- chromenes 7 from simple starting materials was achieved for the first time through ring- closing metathesis/base-induced ring opening/[1, 7]-sigmatropic hydrogen shift reactions. The synthesis of privileged (Z)-2-(buta-1, 3-dienyl) phenols 6 via base-induced ring ...