Synthesis and biological activity of aliphatic and aromatic sulfonic acid azolides

…, ZP Belousova, NA Yakimova, YV Tezikov…

Index: Potapova; Purygin; Lipatov; Belousova; Yakimova; Tezikov; Selezneva Pharmaceutical Chemistry Journal, 2001 , vol. 35, # 11 p. 588 - 590

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Citation Number: 16

Abstract

Previously [1, 2] we synthesized a series of azolides of aliphatic and aromatic sulfonic acids and studied their immunomodulant and cytoprotector properties. In continuation of that work, we have synthesized a series of new aliphatic and aromatic sulfonic acid azolides and evaluated the products with respect to biological activity. The new series includes 2- benzotriazolide (I) and benzimidazolide (II) of methanesulfonic acid and 1, 2, 4-triazolide ( ...