Tetrahedron letters

Synthesis of quinaldines and lepidines by a Doebner–Miller reaction under thermal and microwave irradiation conditions using phosphotungstic acid

G Sivaprasad, R Rajesh, PT Perumal

Index: Sivaprasad, Ganesabaskaran; Rajesh, Rengasamy; Perumal, Paramasivan T. Tetrahedron Letters, 2006 , vol. 47, # 11 p. 1783 - 1785

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Citation Number: 35

Abstract

A simple and efficient method has been developed for the synthesis of quinaldines and lepidines by a one-pot reaction of anilines with crotonaldehyde or methyl vinyl ketone using phosphotungstic acid, a Keggins-type heteropoly acid, under both thermal and microwave irradiation conditions.