Concise and highly selective asymmetric synthesis of acosamine from sorbic acid

SK Bagal, SG Davies, AM Fletcher, JA Lee…

Index: Tetrahedron Letters, , vol. 52, # 17 p. 2216 - 2220

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Citation Number: 46

Abstract

... Tetrahedron Letters. Volume 52, Issue 17, 27 April 2011, Pages 2216–2220. ... 16 In this Letter we report an efficient and highly selective asymmetric synthesis of methyl N,O-diacetyl-α-l- acosaminide in 7 steps from sorbic acid, employing the conjugate addition of lithium (R)-N ...