Journal of the American Chemical Society

Synthesis of cyclic enones via direct palladium-catalyzed aerobic dehydrogenation of ketones

T Diao, SS Stahl

Index: Diao, Tianning; Stahl, Shannon S. Journal of the American Chemical Society, 2011 , vol. 133, # 37 p. 14566 - 14569

Full Text: HTML

Citation Number: 137

Abstract

α, β-Unsaturated carbonyl compounds are versatile intermediates in the synthesis of pharmaceuticals and biologically active compounds. Here, we report the discovery and application of Pd (DMSO) 2 (TFA) 2 as a catalyst for direct dehydrogenation of cyclohexanones and other cyclic ketones to the corresponding enones, using O2 as the oxidant. The substrate scope includes heterocyclic ketones and several natural-product ...

Related Articles:

Iodine (V) reagents in organic synthesis. Part 4. o-Iodoxybenzoic acid as a chemospecific tool for single electron transfer-based oxidation processes

[Journal of the American Chemical Society, , vol. 124, # 10 p. 2245 - 2258]

Regioselective dehydrogenation of 3-keto-steroids to form conjugated enones using o-iodoxybenzoic acid and trifluoroacetic acid catalysis

[Chemistry and Physics of Lipids, , vol. 178, p. 45 - 51]

Steroid derivatives. XXVIII. Preparation of 1-methyl-5α-androstane derivatives

[Collection of Czechoslovak Chemical Communications, , vol. 29, p. 3089 - 3095]

Unusual enolizations in 19-nor-3-ketosteroids

[Journal of the Chemical Society, Chemical Communications, , # 21 p. 1479 - 1481]

More Articles...