Conversion of alcohols to bromides using a fluorous phosphine
L Desmaris, N Percina, L Cottier, D Sinou
Index: Desmaris, Laurence; Percina, Nathalie; Cottier, Louis; Sinou, Denis Tetrahedron Letters, 2003 , vol. 44, # 41 p. 7589 - 7591
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Citation Number: 20
Abstract
Reaction of alcohols with the fluorous phosphine carbon tetrabromide complex in toluene or in a two-phase toluene-FC-72 system afforded the corresponding bromides in good yields. The fluorous-phosphine oxide is readily separated by liquid–liquid extraction, providing an alternative to the homogeneous triphenylphosphine–carbon tetrachloride conversion, as well as to the polymer-supported phosphine method. The fluorous ...
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