Halogenierte Pyridine und 1, 8??Naphthyridine. VI

R Huff, F Mutterer, CD Weis

Index: Huff,R. et al. Helvetica Chimica Acta, 1977 , vol. 60, p. 907 - 921

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Citation Number: 9

Abstract

Summary The principle of the synthesis of 3-halomethyl-2, 6-dichloro-pyridines has been extended to compounds with side chains of more than one carbon atom in the 3-position. Feasible synthetic routes are outlined starting from cheap, commercially available a- methylideneglutaronitrile and trichloroalkyl functional compounds which yield the intermediate 1, 3, 5-trisubstituted alkanes. These are cyclized by aqueous mineral acid or ...