Accounts of chemical research

Asymmetric hydrogenation of prochiral amino ketones to amino alcohols for pharmaceutical use

FD Klingler

Index: Baldwin, Jack E.; Dyer, Robert L.; Ng, Si C.; Pratt, Andrew J.; Russell, Mark A. Tetrahedron Letters, 1987 , vol. 28, # 32 p. 3745 - 3746

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Citation Number: 82

Abstract

... In 1987, he joined the Process Development Department at Boehringer Ingelheim Pharma GmbH & Co., KG, in Germany. ... be marketed as racemates despite the fact that, in the majority of cases, the d- and l-enantiomers have ... Cy,Cy-oxoProNOP, Rh, 92, 10000, 20 bar, 50 °C, 32 h. ...

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