Preparation of 1-substituted hydrazinoacetic acids

J Farkaš, Z Flegelová, V Uchytilová…

Index: Farkas,J. et al. Collection of Czechoslovak Chemical Communications, 1973 , vol. 38, p. 1434 - 1437

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Abstract

In connection with syntheses of some heterocyclic systems, I-methylhydrazinoacetic acid (1) and I-benzylhydrazinoacetic acid (II) were required as the starting material. Only the preparation of the acid I has been mentioned in the literature1; the acid I has also been recently reported as the component of the antibiotic negamycin2• The preparative procedure1 consists in reaction of methylhydrazine with chloroacetic acid, but a great ...