Ring openings of trimetaphosphoric acid and its bismethylene analog. Syntheses of adenosine 5'-bis (dihydroxyphosphinylmethyl) phosphinate and 5'-amino-5'- …

DB Trowbridge, DM Yamamoto…

Index: Trowbridge; Yamamoto; Kenyon Journal of the American Chemical Society, 1972 , vol. 94, # 11 p. 3816 - 3824

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Citation Number: 20

Abstract

Abstract: The reactions of some alcohols with salts of trimetaphosphoric acid in nonaqueous solutions were investigated. Both the ease of ring opening and product distributions were found to be strongly dependent upon whether the solutions were acidic or basic. With acid catalysis, anhydrous methanol reacted with tricyclohexylammonium trimetaphosphate to give methyl phosphate as the only detectable esterified product, even in the early stages ...