Reduction of electron-deficient pyrroles using group I and II metals in ammonia

TJ Donohoe, PM Guyo, RL Beddoes

Index: Donohoe, Timothy J.; Guyo, Paul M.; Beddoes, Roy L.; Helliwell, Madeleine Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 4 p. 667 - 676

Full Text: HTML

Citation Number: 0

Abstract

The preparation and Birch reduction of a series of electron-deficient pyrroles is described. This methodology allows the synthesis of a variety of C-2 substituted 3-pyrrolines []‡ in good to excellent yields. The role of various activating groups (amide, ester, carbamate and urea) has been examined with regard to bot

Related Articles:

Armeniaspiroles, a new class of antibacterials: antibacterial activities and total synthesis of 5-chloro-Armeniaspirole A

[Couturier, Cedric; Bauer, Armin; Rey, Astrid; Schroif-Dufour, Cosima; Broenstrup, Mark Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 19 p. 6292 - 6296]

Synthesis of pyrroloazepines. Facile synthesis of 2??substituted pyrrole derivatives by the phosgene method

[Cho, Hidetsura; Matsuki, Shinsuke; Mizuno, Akira; Annoura, Hirokazu; Tatsuoka, Toshio Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 1 p. 87 - 91]

Synthesis of pyrroloazepines. Facile synthesis of 2??substituted pyrrole derivatives by the phosgene method

[Cho, Hidetsura; Matsuki, Shinsuke; Mizuno, Akira; Annoura, Hirokazu; Tatsuoka, Toshio Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 1 p. 87 - 91]

Design, synthesis and antifungal activities of novel pyrrole alkaloid analogs

[Wang, Ming-Zhong; Xu, Han; Liu, Tuan-Wei; Feng, Qi; Yu, Shu-Jing; Wang, Su-Hua; Li, Zheng-Ming European Journal of Medicinal Chemistry, 2011 , vol. 46, # 5 p. 1463 - 1472]

More Articles...