Super acid catalysed sequential hydrolysis/cycloisomerization of o-(acetylenic) benzamides under microwave condition: Synthesis, antinociceptive and …
C Praveen, P Dheenkumar, PT Perumal
Index: Praveen, Chandrasekaran; Dheenkumar; Perumal Journal of Chemical Sciences, 2013 , vol. 125, # 1 p. 71 - 83
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Citation Number: 6
Abstract
Abstract Synthesis of isocoumarins and related compounds via triflic acid promoted hydrolysis/cyclization sequence of 2-(alkynyl) benzamides under microwave condition was achieved. The substrate scope of the reaction was broad to include not only aromatic but also polyaromatic and heteroaromatic motifs, thus highlighting the significance of this methodology. One-pot operation, short reaction time, good chemical yields and excellent ...
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