Carbohydrate research

A convergent synthesis of trisaccharides with α-Neu5Ac-(2→ 3)-β-d-Gal-(1→ 4)-β-d-GlcNAc and α-Neu5Ac-(2→ 3)-β-d-Gal-(1→ 3)-α-d-GalNAc sequences

J Xia, JL Alderfer, CF Piskorz, RD Locke, KL Matta

Index: Xia, Jie; Alderfer, James L.; Piskorz, Conrad F.; Locke, Robert D.; Matta, Khushi L. Carbohydrate Research, 2000 , vol. 328, # 2 p. 147 - 163

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Citation Number: 8

Abstract

The syntheses of three trisaccharides: α-Neu5Ac-(2→ 3)-β-d-Gal-(1→ 4)-β-d-GlcNAc→ OMe, α-Neu5Ac-(2→ 3)-β-d-Gal6SO3Na-(1→ 4)-β-d-GlcNAc→ OMe, and α-Neu5Ac-(2→ 3)- β-d-Gal-(1→ 3)-α-d-GalNAc→ OBn were accomplished by using either methyl (phenyl 5- acetamido-4, 7, 8, 9-tetra-O-acetyl-3, 5-dideoxy-2-thio-β-d-glycero-d-galacto-2- nonulopyranoside) onate or methyl (phenyl N-acetyl-5-acetamido-4, 7, 8, 9-tetra-O-acetyl- ...