Fatty acid hydroxytyrosyl esters: structure/antioxidant activity relationship by ABTS and in cell-culture DCF assays

…, T Gasperi, S Incerpi, A Gambacorta

Index: Gambacorta, Augusto; Tofani, Daniela; Bernini, Roberta; Migliorini, Antonella Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 9 p. 3386 - 3391

Full Text: HTML

Citation Number: 36

Abstract

A large series of hydroxytyrosyl esters of C2− C18 fatty acids with increasing lipophilicity was prepared by a new highly efficient method based on acylation of methylorthoformate- protected hydroxytyrosol. All products were tested for relative antioxidant effect using ABTS assays in ethanolic medium and DCF assays in L6 cells. No linear correlation between lipophilicity and antioxidant effect was found. ABTS assays showed a growing antioxidant ...

Related Articles:

Efficient synthesis of hydroxytyrosol from 3, 4-dihydroxybenzaldehyde

[Zhang, Zhao-Li; Chen, Jinglei; Xu, Qiongming; Rao, Cui; Qiao, Chunhua Synthetic Communications, 2012 , vol. 42, # 6 p. 794 - 798]

Synthesis of tritium-labeled hydroxytyrosol, a phenolic compound found in olive oil

[Tuck, Kellie L.; Tan, Hai-Wei; Hayball, Peter J. Journal of Agricultural and Food Chemistry, 2000 , vol. 48, # 9 p. 4087 - 4090]

A novel use of the recyclable polymer-supported IBX: an efficient chemoselective and regioselective oxidation of phenolic compounds. The case of hydroxytyrosol …

[Bernini, Roberta; Mincione, Enrico; Crisante, Fernanda; Barontini, Maurizio; Fabrizi, Giancarlo Tetrahedron Letters, 2009 , vol. 50, # 12 p. 1307 - 1310]

Expedient synthesis of hydroxytyrosol and its esters

[Bovicelli, Paolo; Antonioletti, Roberto; Mancini, Silvia; Causio, Stefano; Borioni, Giorgio; Ammendola, Sergio; Barontini, Maurizio Synthetic Communications, 2007 , vol. 37, # 23 p. 4245 - 4252]

Synthesis and structure/antioxidant activity relationship of novel catecholic antioxidant structural analogues to hydroxytyrosol and its lipophilic esters

[Bernini, Roberta; Mincione, Enrico; Barontini, Maurizio; Crisante, Fernanda Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 19 p. 8897 - 8904]

More Articles...