Optimisation of pharmacokinetic properties in a neutral series of 11β-HSD1 inhibitors

JS Scott, AL Gill, L Godfrey, SD Groombridge…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 21 p. 6756 - 6761

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Abstract

... JavaScript is disabled on your browser. Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry Letters. ... 1). 12 In an attempt to increase the chemical diversity of our program, we sought to identify neutral inhibitors of the enzyme. ...

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