Kumada coupling of aryl and vinyl tosylates under mild conditions

ME Limmert, AH Roy, JF Hartwig

Index: Limmert, Michael E.; Roy, Amy H.; Hartwig, John F. Journal of Organic Chemistry, 2005 , vol. 70, # 23 p. 9364 - 9370

Full Text: HTML

Citation Number: 156

Abstract

Aryl and alkenyl tosylates are easily prepared, inexpensive and, thus, attractive for transition- metal-catalyzed couplings, but their reactivity is low. We report examples of mild, palladium- catalyzed coupling of aryl, alkenyl, and alkyl Grignard reagents with aryl and alkenyl tosylates. The resulting biaryls, vinylarenes, and alkylarenes were isolated in good to excellent yield. These couplings were conducted with a nearly equimolar ratio of the two ...

Related Articles:

Suzuki coupling reaction catalyzed heterogeneously by Pd (salen)/polyoxometalate compound: another example for synergistic effect of organic/inorganic hybrid

[Tong, Jinhui; Wang, Haiyan; Cai, Xiaodong; Zhang, Qianping; Ma, Hengchang; Lei, Ziqiang Applied Organometallic Chemistry, 2014 , vol. 28, # 2 p. 95 - 100]

Fast Suzuki–Miyaura cross-coupling reaction catalyzed by the Na 2 Pd 2 Cl 6 complex with ethyl calix [4] aryl acetate at room temperature in aqueous medium under …

[Mu, Bing; Li, Jingya; Han, Zixing; Wu, Yangjie Journal of Organometallic Chemistry, 2012 , vol. 700, p. 117 - 124]

An amphiphilic resin-supported palladium catalyst for high-throughput cross-coupling in water

[Uozumi, Yasuhiro; Nakai, Yasushi Organic Letters, 2002 , vol. 4, # 17 p. 2997 - 3000]

Palladium nanoparticles supported on functional ionic liquid modified magnetic nanoparticles as recyclable catalyst for room temperature Suzuki reaction

[Wang, Jiayi; Xu, Beiling; Sun, Haiyang; Song, Gonghua Tetrahedron Letters, 2013 , vol. 54, # 3 p. 238 - 241]

A simple and efficient tetradentate Schiff base derived palladium complex for Suzuki–Miyaura reaction in water

[Dewan, Anindita; Bora, Utpal; Borah, Geetika Tetrahedron Letters, 2014 , vol. 55, # 10 p. 1689 - 1692]

More Articles...