Synthesis of Coumestrol and Aureol
…, T Xu, E Zhang, X Zhang, W Wei, Y Zou
Index: Zou, Yong; Huang, Qi; Huang, Tong-Kun; Ni, Qing-Chun; Zhang, En-Sheng; Xu, Tian-Long; Yuan, Mu; Li, Jun Organic and Biomolecular Chemistry, 2013 , vol. 11, # 40 p. 6967 - 6974
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Abstract
A total synthesis of coumestrol (1) and aureol (2) is described. The Perkin condensation of 2- bromo-4-hydroxylphenylacetic acid (6) and o-hydroxybenzaldehydes (7) gave the corresponding 2′-bromo-3-arylcoumarins (9). A copper-catalyzed consecutive
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