Synthetic Analogs of Cortical Hormones. II. 3-Substituted α-2, 5-Trihydroxyacetophenone Derivatives

MC Kloetzel, BY Abadir

Index: Kloetzel; Abadir Journal of the American Chemical Society, 1955 , vol. 77, p. 3823,3826

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Citation Number: 4

Abstract

The synthesis and some reactions of 3, 5-diacetoxy-a-diazoacetophenone and of 3-acetoxy- , 3-nitro-and 3-bromo-2, 5-diacetoxy-a-diazoacetophenone have been described. The diazo ketones yielded a-halo ketones by reaction with hydrogen halides, a-ketols by hydrolysis with hot dilute sulfuric acid, and (except for the 3-nitro diazo ketone) a-keto1 acetates by reaction with hot acetic acid. The a-keto1 acetates also were obtained by treatment of the ...