The Journal of Organic Chemistry

Chemical synthesis of some mono-and digalactosyl O-glycopeptides

JM Lacombe, AA Pavia

Index: Lacombe, J. M.; Pavia, A. A. Journal of Organic Chemistry, 1983 , vol. 48, # 15 p. 2557 - 2563

Full Text: HTML

Citation Number: 51

Abstract

Chemical syntheses of several 0-glycopeptides containing 0-galactosylthreonine are reported. Two different approaches have been investigated to determine the strategy best adapted to the synthesis of any desired 0-glycopeptide. Glycosylation of an adequately protected threonine-containing peptide was shown to be less successful than a stepwise strategy using an appropriate 0-glycosyl amino acid as starting material. This route was ...

Related Articles:

Influence of steric parameters on the synthesis of tetramates from α-amino-β-alkoxy-esters and Ph 3 PCCO

[Loke, Inga; Park, Natja; Kempf, Karl; Jagusch, Carsten; Schobert, Rainer; Laschat, Sabine Tetrahedron, 2012 , vol. 68, # 2 p. 697 - 704]

Synthesis of mannosyl and oligomannosyl threonine building blocks found on the Mycobacterium tuberculosis 45 kDa MPT 32 glycoprotein

[Varon, Daniel; Lioy, Eduardo; Patarroyo, Manuel E.; Schratt, Xaver; Unverzagt, Carlo Australian Journal of Chemistry, 2002 , vol. 55, # 1-2 p. 161 - 165]

Influence of steric parameters on the synthesis of tetramates from α-amino-β-alkoxy-esters and Ph 3 PCCO

[Loke, Inga; Park, Natja; Kempf, Karl; Jagusch, Carsten; Schobert, Rainer; Laschat, Sabine Tetrahedron, 2012 , vol. 68, # 2 p. 697 - 704]

More Articles...