Solvent-free copper/iron co-catalyzed N-arylation reactions of nitrogen-containing heterocycles with trimethoxysilanes in air

RJ Song, CL Deng, YX Xie, JH Li

Index: Song, Ren-Jie; Deng, Chen-Liang; Xie, Ye-Xiang; Li, Jin-Heng Tetrahedron Letters, 2007 , vol. 48, # 44 p. 7845 - 7848

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Citation Number: 49

Abstract

A solvent-free copper/iron-catalyzed N-arylation of nitrogen-containing heterocycles with trimethoxysilanes method for the formation of C–N bonds has been developed. In the presence of Cu, FeCl3, TBAF, and air, a variety of nitrogen-containing heterocycles including imidazoles and triazoles were coupled with aryltrimethoxysilanes and vinyltrimethoxysilane to afford the corresponding products in moderate to excellent yields. ...