Quantitative Analysis of the Efficacy and Potency of Novel Small Molecule Ice Recrystallization Inhibitors

S Abraham, K Keillor, CJ Capicciotti…

Index: Capicciotti, Chantelle J.; Trant, John F.; Leclere, Mathieu; Ben, Robert N. Bioconjugate Chemistry, 2011 , vol. 22, # 4 p. 605 - 616

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Abstract

We present a new method for quantifying ice recrystallization inhibition activity via a kinetic approach. We have derived first-order rate constants for the increase in the average crystal size based upon a “binning” approach of ice crystals as a function of size and time. From

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