Environmentally benign synthesis of Indeno [1, 2-b] quinolines via an Intramolecular Povarov Reaction

M Chen, N Sun, Y Liu

Index: Chen, Ming; Sun, Ning; Liu, Yuanhong Organic Letters, 2013 , vol. 15, # 21 p. 5574 - 5577

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Citation Number: 18

Abstract

A new synthetic route to indeno [1, 2-b] quinolines via reactions of o- propargylbenzaldehydes with N-aryl amines based on an intramolecular aza-Diels–Alder (Povarov) reaction has been developed. This method offers several advantages such as no requirement for an oxidant, high efficiency, and a wide reaction scope.