Silver compounds in synthetic chemistry: Part 5: Selective syntheses of trifluoromethylketones, RCOCF3, from trifluoromethylsilver, AgCF3, and corresponding acyl …

MM Kremlev, AI Mushta, W Tyrra, D Naumann…

Index: Kremlev, Mikhail M.; Mushta, Aleksej I.; Tyrra, Wieland; Naumann, Dieter; Fischer, Hendrik T.M.; Yagupolskii, Yurii L. Journal of Fluorine Chemistry, 2007 , vol. 128, # 11 p. 1385 - 1389

Full Text: HTML

Citation Number: 23

Abstract

Trifluoromethylketones of aromatics, heteroaromatics and olefins are formed selectively from reactions of trifluoromethylsilver and the corresponding carboxylic acid chlorides in moderate to excellent yields. The conditions chosen are dependent on the nature of the acyl chloride. Attempts to prepare alkyl (trifluoromethyl) ketones yielded product mixtures of the corresponding acyl fluorides, trifluoromethyl-, pentafluoroethyl-and n-heptafluoropropyl ...

Related Articles:

A new entry for the oxidation of fluoroalkyl-substituted methanol derivatives: Scope and limitation of the organoiodine (V) reagent-catalyzed oxidation

[Tanaka, Yusuke; Ishihara, Takashi; Konno, Tsutomu Journal of Fluorine Chemistry, 2012 , vol. 137, p. 99 - 104]

Direct preparation of trifluoromethyl ketones from carboxylic esters: trifluoromethylation with (trifluoromethyl) trimethylsilane

[Wiedemann, Juergen; Heiner, Thomas; Mloston, Gregorz; Prakash, G.K. Surya; Olah, George A. Angewandte Chemie - International Edition, 1998 , vol. 37, # 6 p. 820 - 821]

Highly efficient synthesis of aryl and heteroaryl trifluoromethyl ketones via o-iodobenzoic acid (IBX)

[Cheng, Huicheng; Pei, Yu; Leng, Faqiang; Li, Jingya; Liang, Apeng; Zou, Dapeng; Wu, Yangjie; Wu, Yusheng Tetrahedron Letters, 2013 , vol. 54, # 33 p. 4483 - 4486]

More Articles...