Tetrahedron letters

High stereoselective synthesis of diethyl (2, 3-isopropylidene-5-trityl-α-d-ribofuranosyl)-methanephosphonate, a precursor to the phosphono analog of α-d-ribose 1- …

F Nicotra, L Panza, F Ronchetti, L Toma

Index: Nicotra, Francesco; Panza, Luigi; Ronchetti, Fiamma; Toma, Lucio Tetrahedron Letters, 1984 , vol. 25, # 51 p. 5937 - 5938

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Citation Number: 19

Abstract

Abstract The reaction of 2, 3-isopropylidene-5-trityl-d-ribofuranose with methylenetriphenyl- phosphorane and the subsequent mercuriocyclization, iodomercuriation and Arbuzov reaction, allow a highly stereoselective entry to the phosphono analog of α-d-ribose 1- phosphate.

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