Imidazo [1, 2-a] pyridine anthelmintic and antifungal agents

MH Fisher, A Lusi

Index: Fisher,M.H.; Lusi,A. Journal of Medicinal Chemistry, 1972 , vol. 15, p. 982 - 985

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Citation Number: 128

Abstract

K, CO,, and 0.7 ml (O. 011 mole). of Me1 in 50 ml of Me, CO was stirred at room temp for 24 hr. The mixt was filtered, and the filtrate concd under reduced pressure to 2.6 g of a mixt of crystals and brown liquid. Chromatography on prep tlc plates provided three fractions. The least polar fraction gave 0.23 g of a tacky solid which was recrystd (hexane) to give 0.059 g (2.7%) of straw-colored crystals, mp 56-70". An additional recrystn (pentane) provided