Influence of the solvent on the action of ammonia on halogeno??derivatives of pyridine and nitrobenzene

HJ Den Hertog, C Jouwersma

Index: den Hertog; Jouwersma Recueil des Travaux Chimiques des Pays-Bas, 1953 , vol. 72, p. 44,47

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Citation Number: 7

Abstract

Abstract The reactivity of 2, 4, 6-tribromopyridine-towards dilute solutions of ammonia in water and butanol is described. The rate of the substitution reaction is higher in water than in the less polar butanol. In water the reagent attacks chiefly the bromine atom at the 4- position, where the nucleus carries the highest positive electrical charge. In butanol the replacement of the bromine atoms at the 2-and 6-positions is preponderant. Together with ...