Synthetic communications

Simple synthesis of versatile coumarin scaffolds

L Polito, M Cravini, L Poletti, L Lay

Index: Polito, Laura; Cravini, Massimiliano; Poletti, Laura; Lay, Luigi Synthetic Communications, 2006 , vol. 36, # 15 p. 2203 - 2209

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Citation Number: 15

Abstract

Abstract We describe an approach using ring??closing metathesis (RCM) to synthesize versatile coumarin derivatives that present appropriate substitutions both at the aromatic and at the α, β??unsaturated lactone ring. The obtained compounds can be used as molecular scaffolds suitable for further diversifications through a combinatorial approach.

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