Syntheses of derivatives of oestrane and 19-norsteroids from 6-methoxytetralone and 6-hydroxytetralone

SN Ananchenko, YY Limanov, VN Leonov…

Index: Ananchenko,S.N. et al. Tetrahedron, 1962 , vol. 18, p. 1355 - 1367

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Citation Number: 61

Abstract

The corresponding derivatives of Δ1, 3, 5 (10), 9,(11)-8, 14-seco-d-homo-oestratetraen-3-ol- 14, 17a-dione (VII, VIII, IX) have been obtained by the condensation of 3-methoxy-, 3- hydroxy-, and 3-tetrahydropyranyloxy-1-vinyltetralols (IV, V, VI) with methyldihydroresorcinol. The diketones VIII and IX cyclize to form Δ1, 3, 5 (10), 8, 14-d-homo-oestrapentaen-3-ol-17a- one (XIII), and the diketone (VII) may be converted, according to conditions, into 3- ...