Synthesis

A convenient and improved Baylis-Hillman synthesis of 3-substituted 2H-1-benzopyran-2-ones

PT Kaye, MA Musa

Index: Kaye, Perry T.; Musa, Musiliyu A. Synthesis, 2002 , # 18 p. 2701 - 2706

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Citation Number: 24

Abstract

Abstract Halogen acid-catalysed deprotection and cyclisation of Baylis-Hillman products obtained using O-benzylated salicylaldehyde precursors has been shown to afford 3- (halomethyl) coumarins (3-halomethyl-2H-1-benzopyran-2-ones) chemoselectively and in good yield.

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