Synthesis of alkyl-substituted pyrroles by three-component coupling of carbonyl compound, amine and nitro-alkane/alkene on a solid surface of silica gel/alumina …

BC Ranu, A Hajra

Index: Ranu, Brindaban C; Hajra, Alakananda Tetrahedron, 2001 , vol. 57, # 22 p. 4767 - 4773

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Citation Number: 69

Abstract

Efficient synthesis of highly substituted alkylpyrroles and fused pyrroles has been achieved by a three-component coupling of (a) α, β-unsaturated aldehyde/ketone, amine and nitroalkane and (b) α, β-unsaturated nitroalkene, aldehyde/ketone and amine on the surface of silica gel and alumina without any solvent under microwave irradiation.