Synthesis of substituted benzo [d] thiazol-2-ylcarbamates as potential anticonvulsants

A Navale, S Pawar, M Deodhar, A Kale

Index: Navale, Ashvini; Pawar, Smita; Deodhar, Meenakshi; Kale, Amol Medicinal Chemistry Research, 2013 , vol. 22, # 9 p. 4316 - 4321

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Citation Number: 7

Abstract

Abstract A series of substituted benzo [d] thiazol-2-ylcarbamates 4a–g and 5a–g were synthesized and evaluated for anticonvulsant activity. The structures of the synthesized compounds were confirmed on the basis of their physical and spectral data. The compounds were evaluated for anticonvulsant activity using PTZ-induced convulsion and maximal electroshock models. The target compounds have shown significant activity in these ...