α-Oxygenated Pyridines. II. The Synthesis of 3-Hydroxymethyl-6-methyl-2-pyridol, an Isomer of 4-Deshydroxymethylpyridoxin1

RP Mariella, AJ Havlik

Index: Mariella; Havlik Journal of the American Chemical Society, 1952 , vol. 74, p. 1915

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Citation Number: 9

Abstract

Hydrolysis of I gave 3-carboxy-6-methyl-2 (1)-pyridone (IV). In view of the SUCC~ SS~~~~ of the conversion of heterocyclic esters to alcohols with lithium aluminum hydride, IV was converted into V by using diazomethane, but the reduction of V to VI1 was not successful. It was later found that it was possible to reduce IV directly to VII.