Tetrahedron

One-pot synthesis of substituted 3-amino-2-nitrothiophenes and selenophenes

D Thomae, JCR Dominguez, G Kirsch, P Seck

Index: Thomae, David; Rodriguez Dominguez, Juan Carlos; Kirsch, Gilbert; Seck, Pierre Tetrahedron, 2008 , vol. 64, # 14 p. 3232 - 3235

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Citation Number: 14

Abstract

In this work, we described an easy preparation of substituted 3-amino-2-nitrothiophenes and selenophenes. Substituted β-chloroacrylonitriles were reacted with sodium sulfide or sodium selenide and bromonitromethane to yield the expected compounds in a one-pot three-step procedure in good yields.