Tetrahedron

The diterpene alkaloids: the structure and stereochemistry of heteratisine

R Aneja, DM Locke, SW Pelletier

Index: Aneja,R. et al. Tetrahedron, 1973 , vol. 29, p. 3297 - 3308

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Citation Number: 14

Abstract

Chemical and spectroscopic studies have shown that heteratisine (C22H33NO5), a diterpene lactone alkaloid occurring as a monobenzoyl ester in the roots of Aconitum heterophyllum Wall, has stereostructure 1. Heteratisine thus bears a closer structural relationship to the highly toxic and polyoxygenated alkaloids of the lycoctonine-aconitine type than to its companion bases of A. heterophyllum, atisine, atidine and hetisine. An ...