(-)-4-Hydroxymorphinanones: their synthesis and analgesic activity
A Manmade, HC Dalzell, JF Howes…
Index: Manmade; Dalzell; Howes; Razdan Journal of Medicinal Chemistry, 1981 , vol. 24, # 12 p. 1437 - 1440
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Citation Number: 13
Abstract
The antinociceptive activity of these compounds is shown in Table I. It was determined both in the acetic acid induced mouse writhings and the heat stimulus rat tail-flickg tests. The narcotic antagonist activity was determined by the rat tail-flick methode against an EDw of morphine.
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