Tetrahedron letters

Lithiation of the dimer of 3-bromo-6-dimethylamino-1-azafulvene. efficacious synthesis of 4-mono-and 4, 5-disubstituted pyrrole-2-carboxaldehydes

JM Muchowski, P Hess

Index: Muchowski, Joseph M.; Hess, Petr Tetrahedron Letters, 1988 , vol. 29, # 26 p. 3215 - 3218

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Citation Number: 14

Abstract

In conclusion. it has been shown that the readily available dimer J& of 3-bromod- dimethylamino-1-azafulvene. serves as a formal equivalent of either 4-lithio-or 4.5- dilithiopyrrole-2-carboxaldehyde, and as such, it can provide access to an irmnense variety of pyrrole-2-carboxaldehyde derivatives, with an efficiency and economy of steps unmatched by any published procedure".