Phenylfurans IV: Spasmolytic 3??diethylamino??2, 2??(dimethyl) propyl esters of 5??substituted phenyl??2??furancarboxylic acids

HA Burch, RE White, GC Wright…

Index: Burch; White; Wright; Goldenberg Journal of Pharmaceutical Sciences, 1980 , vol. 69, # 1 p. 107 - 110

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Citation Number: 31

Abstract

Abstract A series of 3-diethylamino-2, 2-(dimethyl) propyl 5-substituted phenyl-2- furancarboxylates was prepared and found to be pharmacologically active in vitro as GI tract nonanticholinergic smooth muscle spasmolytic agents. One of the more active compounds in the series contained the 5-(4-nitrophenyl) group.

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